An evolutionary model to predict the frequency of antibiotic resistance under seasonal antibiotic use, and an application to Streptococcus pneumoniae

F Blanquart, S Lehtinen… - Proceedings of the …, 2017 - royalsocietypublishing.org
temporal averages of use of each of these antibiotics. We consider temporal variations in
antibiotic use … For penicillin resistance in the Jewish children, where the coefficient was highest …

Modeling the effect of vaccination on selection for antibiotic resistance in Streptococcus pneumoniae

NG Davies, S Flasche, M Jit, KE Atkins - Science translational medicine, 2021 - science.org
… and penicillin nonsusceptibility in Streptococcus pneumoniae (… We show that the frequency
of penicillin resistance in S. … other is temporal: Although, in individual countries, resistance

Exploring factors shaping antibiotic resistance patterns in Streptococcus pneumoniae during the 2020 COVID-19 pandemic

A Kovacevic, DRM Smith, E Rahbé, S Novelli… - Elife, 2024 - elifesciences.org
… in pneumococcal resistance to both penicillin and macrolides between 2019 and 2020. The
… dynamics of antibiotic resistance in S. pneumoniae, we propose a mathematical model that …

[HTML][HTML] Improved penicillin susceptibility of Streptococcus pneumoniae and increased penicillin consumption in Japan, 2013–18

S Tsuzuki, T Akiyama, N Matsunaga, K Yahara… - Plos one, 2020 - journals.plos.org
… pneumonias and bloodstream infections, because it will be unlikely to induce penicillin
resistance, and the use of total antibiotics and cephalosporins is more strongly associated with a …

Antimicrobial Resistance Among Streptococcus pneumoniae

C Cillóniz, C Garcia-Vidal, A Ceccato… - Antimicrobial Resistance in …, 2018 - Springer
… of fluoroquinolones in children is limited, because in animal models using young animals, …
[61] regarding the duration of previous antibiotic treatment and its association with penicillin-…

[HTML][HTML] Dynamics of Antibiotic Resistance of Streptococcus pneumoniae in France: A Pediatric Prospective Nasopharyngeal Carriage Study from 2001 to 2022

A Rybak, C Levy, N Ouldali, S Bonacorsi, S Béchet… - Antibiotics, 2023 - mdpi.com
resistant to penicillin) but more pronounced for PCV20 (serotypes 15BC and 11A are among
the most carried and often antibiotic resistant). … Using a segmented regression model, we …

[HTML][HTML] Temporal relationship between antibiotic use and respiratory virus activities in the Republic of Korea: a time-series analysis

S Ryu, S Kim, BI Kim, EY Klein, YK Yoon… - Antimicrobial Resistance …, 2018 - Springer
… analysis using the residuals from each time-series model … a strong temporal association
between antibiotic use, and … between antibiotic use of common antibiotics (penicillins, other …

Antibiotics and antimicrobial resistance: temporal and global trends in the environment

K Rehman, F Fiayyaz, M Khurshid, S Sabir… - … Antimicrobial Resistance …, 2020 - Elsevier
… , Staphylococcus aureus, and Streptococcus pneumoniae temporally and globally. Among
… In the search for new antimicrobial agents, the microbial bioactive compounds are nowhere …

Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae

S Lehtinen, C Chewapreecha, J Lees, WP Hanage… - Science …, 2020 - science.org
models to test which aggregator is the best predictor of the three traits of interest and found
that models … HGT and resistance (7, 12–14) spanned different spatial and temporal scales …

Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction

ER Watkins, A Kalizang'Oma, A Gori, S Gupta… - Trends in …, 2022 - cell.com
… Mathematical models simulating the effects of pneumococcal vaccination on AMR have …
of co-colonisation, exposure to antibiotics, as well as the cost of resistance and country-specific …